SELEX-on-a-Chip: Microchip Integration of the Sol-Gel Derived Affinity Column for Monitoring RNA-Protein Interaction
نویسندگان
چکیده
A microfluidic chip that integrates a sol-gel derived affinity column with a microheater is developed. This microchip includes five electric heaters covered with patterned PMMA for individual heat elution from five sol-gels with target molecules. This study is the first to demonstrate the detection of proteinaptamer interactions on the sol-gel microfluidic system and further describes possible compatibility with Systematic Evolution of Ligands by Exponential Enrichment (SELEX).
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